NAD+ for Healthy Aging
As we age, our bodies naturally produce less NAD+—a vital coenzyme that powers cellular energy, DNA repair, and metabolic function. NAD+ Therapy at Hydrate Medical offers a provider-guided approach to supporting your body’s cellular health as you age.
We provide NAD+ infusions and subcutaneous (subQ) injections under medical supervision as part of a comprehensive wellness approach—not as a cure for aging, but as supportive care for cellular vitality.
Who This May Help
- Adults experiencing age-related fatigue or reduced energy
- Individuals seeking to support healthy cellular function
- People interested in proactive wellness as they age
- Those looking for medically supervised metabolic support
What the Research Shows
NAD+ levels naturally decline with age—by midlife, cellular NAD+ can drop by approximately 50%. Research suggests this decline may contribute to various age-related changes in cellular function.
A 2018 study published in Nature Communications found that supplementation with the NAD+ precursor nicotinamide riboside in healthy middle-aged and older adults (ages 55-79) was well-tolerated and effectively elevated NAD+ levels. The study also showed a trend toward reduced blood pressure and arterial stiffness in participants, particularly those with elevated baseline blood pressure.
Similarly, a 2023 randomized, double-blind, placebo-controlled trial published in Scientific Reports found that 12 weeks of NAD+ precursor supplementation showed trends toward reduced arterial stiffness in healthy middle-aged adults, with statistically significant improvements in participants with higher body mass index or elevated blood glucose levels.
Important Context:
While animal studies have shown promising anti-aging effects from NAD+ restoration, human clinical trials are still emerging. Most evidence to date demonstrates that NAD+ precursors can successfully raise NAD+ levels in humans and may support certain markers of vascular health—but long-term anti-aging benefits in humans require further research.
What We Offer
NAD+ IV Infusions
Deep cellular replenishment delivered in a calm, supervised environment. Each infusion is customized to your health profile and goals.
- Duration: 4–6 hours per session in our relaxing lounge
- Administration: Licensed RN-supervised with continuous monitoring
- Frequency: Provider-determined based on your response and objectives
NAD+ SubQ Injections
Convenient subcutaneous injections for ongoing maintenance or those seeking a faster alternative to IV therapy.
- Duration: Quick in-clinic visits
- Flexibility: Can be self-administered with provider guidance
- Use: Often scheduled as follow-up to IV series or standalone maintenance
What to Expect
Before Your Visit:
- Health history review including medications and current conditions
- Discussion of realistic goals and expected outcomes
- Eligibility screening with our medical team
During Treatment:
- Comfortable lounge setting with streaming, refreshments, and privacy
- Continuous monitoring by licensed nursing staff
- Adjustable infusion rate based on your tolerance
After Treatment:
- Clear aftercare instructions
- Follow-up scheduling based on your personalized plan
- Optional lab work to track biomarkers over time
Safety & Medical Oversight
- Medical Director oversight with licensed NPs/PAs/RNs
- Comprehensive eligibility screening—not everyone is a candidate
- Sterile, single-use medical supplies and established safety protocols
- Monitoring for potential side effects (rare but may include nausea, flushing, or discomfort at infusion site)
Realistic Expectations
NAD+ therapy is not a fountain of youth. Aging is a complex biological process influenced by genetics, lifestyle, environment, and numerous other factors. While research suggests NAD+ restoration may support certain cellular functions, we cannot guarantee specific anti-aging outcomes.
What NAD+ May Support:
- Cellular energy production and mitochondrial function
- Natural DNA repair processes
- Metabolic efficiency
- Cardiovascular health markers (based on preliminary research)
What NAD+ Cannot Do:
- Reverse aging or extend lifespan (not proven in humans)
- Replace healthy lifestyle habits like diet and exercise
- Treat diagnosed age-related diseases without other medical interventions
Frequently Asked Questions
Visit Us
Hydrate Medical serves communities across North Carolina and South Carolina. Availability of IV ketamine may vary by location. Please contact us to confirm service at your nearest clinic.
Hydrate Medical® provides wellness services under clinical oversight. Content is educational and not a substitute for personalized medical advice. Individual results vary. NAD+ therapy is not FDA-approved as an anti-aging treatment.
